AAK1 Antikörper (AA 274-465)
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- Target Alle AAK1 Antikörper anzeigen
- AAK1 (AP2 associated kinase 1 (AAK1))
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Bindungsspezifität
- AA 274-465
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser AAK1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human, Maus
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human AP2-associated protein kinase 1 protein (274-465AA)
- Isotyp
- IgG
- Top Product
- Discover our top product AAK1 Primärantikörper
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anti-AP2 associated kinase 1 (AAK1) (AA 315-415) antibody
AAK1 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 4B10 unconjugated
anti-AP2 associated kinase 1 (AAK1) (C-Term) antibodyAAK1 Reaktivität: Human, Maus, Ratte WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-AP2 associated kinase 1 (AAK1) (N-Term) antibodyAAK1 Reaktivität: Human, Maus, Ratte WB, IHC, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-AP2 associated kinase 1 (AAK1) (N-Term) antibodyAAK1 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-AP2 associated kinase 1 (AAK1) (AA 301-400) antibodyAAK1 Reaktivität: Maus ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-AP2 associated kinase 1 (AAK1) antibodyAAK1 Reaktivität: Human, Maus, Ratte, Rind (Kuh) WB, IHC, IF, IC Wirt: Kaninchen Polyclonal unconjugated
anti-AP2 associated kinase 1 (AAK1) (Internal Region) antibodyAAK1 Reaktivität: Human, Maus, Ratte, Affe WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-AP2 associated kinase 1 (AAK1) (AA 186-216), (N-Term) antibodyAAK1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB16487 unconjugated
anti-AP2 associated kinase 1 (AAK1) (AA 790-819), (C-Term) antibodyAAK1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB16779 unconjugated
anti-AP2 associated kinase 1 (AAK1) (Internal Region) antibodyVerified AAK1 Reaktivität: Human WB, ELISA Wirt: Ziege Polyclonal unconjugated
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- Applikationshinweise
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- AAK1 (AP2 associated kinase 1 (AAK1))
- Andere Bezeichnung
- AAK1 (AAK1 Produkte)
- Hintergrund
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Background: Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2) which ensures high affinity binding of AP-2 to cargo membrane proteins during the initial stages of endocytosis. Isoform 1 and isoform 2 display similar levels of kinase activity towards AP2M1. Regulates phosphorylation of other AP-2 subunits as well as AP-2 localization and AP-2-mediated internalization of ligand complexes. Phosphorylates NUMB and regulates its cellular localization, promoting NUMB localization to endosomes. Binds to and stabilizes the activated form of NOTCH1, increases its localization in endosomes and regulates its transcriptional activity.
Aliases: AAK 1 antibody, Aak1 antibody, AAK1_HUMAN antibody, Adaptor associated kinase 1 antibody, Adaptor-associated kinase 1 antibody, AP2 associated kinase 1 antibody, AP2 associated protein kinase 1 antibody, AP2-associated protein kinase 1 antibody, DKFZp686F03202 antibody, DKFZp686K16132 antibody, FLJ23712 antibody, FLJ25931 antibody, FLJ31060 antibody, FLJ42882 antibody, FLJ45252 antibody, KIAA1048 antibody, MGC138170 antibody, MGC164568 antibody, MGC164570 antibody
- UniProt
- Q2M2I8
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