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APP Antikörper

APP Reaktivität: Human WB, ELISA, IHC, IF Wirt: Maus Monoclonal 5A11E5 unconjugated
Produktnummer ABIN7144489
  • Target Alle APP Antikörper anzeigen
    APP (Amyloid beta (A4) Precursor Protein (APP))
    Reaktivität
    • 229
    • 110
    • 106
    • 12
    • 10
    • 10
    • 9
    • 9
    • 9
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 195
    • 72
    • 4
    • 4
    • 1
    Maus
    Klonalität
    • 213
    • 63
    Monoklonal
    Konjugat
    • 142
    • 24
    • 19
    • 18
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser APP Antikörper ist unkonjugiert
    Applikation
    • 177
    • 127
    • 74
    • 52
    • 52
    • 44
    • 38
    • 29
    • 28
    • 15
    • 15
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Kreuzreaktivität
    Human, Maus
    Aufreinigung
    Protein G purified
    Immunogen
    Recombinant Human APP Protein
    Klon
    5A11E5
    Top Product
    Discover our top product APP Primärantikörper
  • Applikationshinweise
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:500, IF:1:50-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    APP (Amyloid beta (A4) Precursor Protein (APP))
    Andere Bezeichnung
    APP (APP Produkte)
    Hintergrund

    Background: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

    Aliases: Amyloid Beta (A4) Precursor Protein, ABPP, APP, Beta-Amyloid Peptide

    UniProt
    P05067
    Pathways
    Caspase Kaskade in der Apoptose, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour
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