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ARPIN Antikörper (AA 1-226)

Reaktivität: Human ELISA, WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7144631
  • Target Alle ARPIN Antikörper anzeigen
    ARPIN
    Bindungsspezifität
    • 4
    • 2
    • 1
    AA 1-226
    Reaktivität
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 8
    Kaninchen
    Klonalität
    • 8
    Polyklonal
    Konjugat
    • 4
    • 2
    • 1
    • 1
    Dieser ARPIN Antikörper ist unkonjugiert
    Applikation
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Arpin protein (1-226AA)
    Isotyp
    IgG
  • Applikationshinweise
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    ARPIN
    Abstract
    ARPIN Produkte
    Synonyme
    actin-related protein 2/3 complex inhibitor antikoerper, actin related protein 2/3 complex inhibitor antikoerper, actin related protein 2/3 complex inhibitor L homeolog antikoerper, Arpin antikoerper, ARPIN antikoerper, arpin.L antikoerper
    Hintergrund

    Background: Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex, the function is competetive with nucleation promoting factors. Participates in an incoherent feedforward loop at the lamellipodium tip where it inhibits the ARP2/2 complex in response to Rac signaling and where Rac also stimulates actin polymerization through the WAVE complex. Involved in steering cell migration by controlling its directional persistence.

    Aliases: 2610034B18Rik antibody, Actin related protein 2/3 complex inhibitor antibody, Arp2/3 inhibition protein antibody, ARPIN antibody, C15orf38 antibody, Chromosome 15 open reading frame 38 antibody, CO038_HUMAN antibody, Hypothetical protein LOC348110 antibody, MGC61550 antibody, RIKEN cDNA 2610034B18 antibody, UPF0552 protein C15orf38 antibody

    UniProt
    Q7Z6K5
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