Axin Antikörper (AA 418-707)
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- Target Alle Axin (AXIN1) Antikörper anzeigen
- Axin (AXIN1) (Axin 1 (AXIN1))
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Bindungsspezifität
- AA 418-707
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Axin Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Axin-1 protein (418-707AA)
- Isotyp
- IgG
- Top Product
- Discover our top product AXIN1 Primärantikörper
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anti-Axin 1 (AXIN1) (AA 546-752) antibody
AXIN1 Reaktivität: Human ELISA, ICC, FACS Wirt: Maus Monoclonal 4E9F1 unconjugated
anti-Axin 1 (AXIN1) (AA 618-827) antibodyAXIN1 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Axin 1 (AXIN1) (AA 643-740) antibodyAXIN1 Reaktivität: Human WB, ELISA, IF, PLA Wirt: Maus Monoclonal 2B11 unconjugated
anti-Axin 1 (AXIN1) (AA 470-570) antibody (Atto 488)AXIN1 Reaktivität: Human, Ratte WB, IHC Wirt: Kaninchen Polyclonal Atto 488
anti-Axin 1 (AXIN1) (AA 470-570) antibody (Atto 594)AXIN1 Reaktivität: Human, Ratte WB, IHC Wirt: Kaninchen Polyclonal Atto 594
anti-Axin 1 (AXIN1) (AA 470-570) antibody (Atto 390)AXIN1 Reaktivität: Human, Ratte WB, IHC Wirt: Kaninchen Polyclonal Atto 390
anti-Axin 1 (AXIN1) (AA 546-752) antibodyAXIN1 Reaktivität: Human ELISA Wirt: Maus Monoclonal 4F10G1 unconjugated
anti-Axin 1 (AXIN1) (AA 470-570) antibody (FITC)AXIN1 Reaktivität: Human, Ratte WB, IHC Wirt: Kaninchen Polyclonal FITC
anti-Axin 1 (AXIN1) (AA 653-862) antibodyAXIN1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Axin 1 (AXIN1) (AA 710-738), (C-Term) antibodyAXIN1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB31751 unconjugated
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- Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- Axin (AXIN1) (Axin 1 (AXIN1))
- Andere Bezeichnung
- AXIN1 (AXIN1 Produkte)
- Hintergrund
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Background: Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects, down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. In Wnt signaling, probably facilitates the phosphorylation of CTNNB1 and APC by GSK3B. Likely to function as a tumor suppressor. Facilitates the phosphorylation of TP53 by HIPK2 upon ultraviolet irradiation. Enhances TGF-beta signaling by recruiting the RNF111 E3 ubiquitin ligase and promoting the degradation of inhibitory SMAD7. Also component of the AXIN1-HIPK2-TP53 complex which controls cell growth, apoptosis and development.
Aliases: AI316800 antibody, AXIN antibody, Axin 1 antibody, Axin-1 antibody, axin1 antibody, AXIN1_HUMAN antibody, Axis inhibition protein 1 antibody, Axis Inhibitor 1 antibody, Fu antibody, fused antibody, Fused, mouse, homolog of antibody, hAxin antibody, Kb antibody, Ki antibody, kinky antibody, knobbly antibody, MGC132911 antibody, MGC52315 antibody, PPP1R49 antibody, Protein Fused antibody, Protein phosphatase 1 regulatory subunit 49 antibody
- UniProt
- O15169
- Pathways
- WNT Signalweg, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling
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