CD79a Antikörper (AA 70-142)

Produktnummer ABIN7145141

Produktdetails anti-CD79a Antikörper

Target: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Bindungsspezifität: AA 70-142

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD79a Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human B-cell antigen receptor complex-associated protein alpha chain protein (70-142AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CD79a

Target: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Andere Bezeichnung: CD79A (CD79A Produkte)

Synonyme: CD79A antikoerper, Ig-alpha antikoerper, Iga antikoerper, Igalpha antikoerper, Ly-54 antikoerper, Ly54 antikoerper, mb-1 antikoerper, IGA antikoerper, MB-1 antikoerper, IG-alpha antikoerper, CD79a molecule antikoerper, CD79A antigen (immunoglobulin-associated alpha) antikoerper, Cd79a molecule-like antikoerper, CD79A antikoerper, Cd79a antikoerper, Cd79al antikoerper

Hintergrund:

Background: Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.

Aliases: B lymphocyte-specific MB1 protein antibody, B-cell antigen receptor complex-associated protein alpha chain antibody, CD 79a antibody, CD79a antibody, CD79a antigen (immunoglobulin-associated alpha) antibody, CD79A antigen antibody, CD79a molecule, immunoglobulin-associated alpha antibody, CD79A_HUMAN antibody, Ig alpha antibody, Ig-alpha antibody, IGA antibody, IgM-alpha antibody, Immunoglobulin-associated alpha antibody, Ly54 antibody, MB-1 membrane glycoprotein antibody, MB1 antibody, Membrane-bound immunoglobulin-associated protein antibody, Surface IgM-associated protein antibody

UniProt: P11912

Pathways: BCR Signaling