BANF1 Antikörper (AA 2-89)
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- Target Alle BANF1 Antikörper anzeigen
- BANF1 (Barrier To Autointegration Factor 1 (BANF1))
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Bindungsspezifität
- AA 2-89
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser BANF1 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Barrier-to-autointegration factor protein (2-89AA)
- Isotyp
- IgG
- Top Product
- Discover our top product BANF1 Primärantikörper
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- Applikationshinweise
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- BANF1 (Barrier To Autointegration Factor 1 (BANF1))
- Andere Bezeichnung
- BANF1 (BANF1 Produkte)
- Hintergrund
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Background: Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging. Exploited by retroviruses for inhibiting self-destructing autointegration of retroviral DNA, thereby promoting integration of viral DNA into the host chromosome. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD.
Aliases: BAF antibody, BAF_HUMAN antibody, BANF 1 antibody, BANF1 antibody, Barrier to autointegration factor 1 antibody, Barrier to autointegration factor antibody, Barrier-to-autointegration factor antibody, BCRG 1 antibody, BCRG1 antibody, BCRP 1 antibody, BCRP1 antibody, Breakpoint cluster region protein 1 antibody, D14S1460 antibody, MGC111161 antibody, NGPS antibody
- UniProt
- O75531
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