DEFB126 Antikörper (AA 36-111)

Produktnummer ABIN7145480

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DEFB126 in ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für DEFB126 Antikörper (AA 36-111) (ABIN7145480)

Target: DEFB126 (Defensin, beta 126 (DEFB126))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DEFB126 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-DEFB126 Antikörper

Bindungsspezifität: AA 36-111

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Beta-defensin 126 protein (36-111AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DEFB126

Target: DEFB126 (Defensin, beta 126 (DEFB126))

Andere Bezeichnung: DEFB126

Hintergrund:

Background: Highly glycosylated atypical beta-defensin involved in several aspects of sperm function. Facilitates sperm transport in the female reproductive tract and contributes to sperm protection against immunodetection, both functions are probably implicating the negative surface charge provided by its O-linked oligosaccharides in the sperm glycocalyx. Involved in binding of sperm to oviductal epithelial cells to form a sperm reservoir until ovulation. Release from the sperm surface during capacitation and ovaluation by an elevation of oviductal fluid pH is unmasking other surface components and allows sperm to penetrate the cumulus matrix and bind to the zona pellucida of the oocyte (By similarity). In vitro has antimicrobial activity and may inhibit LPS-mediated inflammation (PubMed:19373462, PubMed:23229569).

Aliases: DEFB126 antibody, C20orf8 antibody, DEFB26Beta-defensin 126 antibody, Beta-defensin 26 antibody, DEFB-26 antibody, Defensin antibody, beta 126 antibody, Epididymal secretory protein 13.2 antibody, ESP13.2 antibody, HBD26 antibody

UniProt: Q9BYW3