NDST1 Antikörper (AA 40-556) (Biotin)

Produktnummer ABIN7145571

Produktdetails anti-NDST1 Antikörper (Biotin)

Target: NDST1 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1))

Bindungsspezifität: AA 40-556

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NDST1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 protein (40-556AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu NDST1

Target: NDST1 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1))

Andere Bezeichnung: NDST1 (NDST1 Produkte)

Hintergrund:

Background: Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L-selectin ligands, thereby playing a role in inflammatory response.

Aliases: NDST1 antibody, HSST antibody, HSST1 antibody, Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 antibody, EC 2.8.2.8 antibody, Glucosaminyl N-deacetylase/N-sulfotransferase 1 antibody, NDST-1 antibody, N-heparan sulfate sulfotransferase 1 antibody, N-HSST 1 antibody, [Heparan sulfate]-glucosamine N-sulfotransferase 1 antibody, HSNST 1) [Includes: Heparan sulfate N-deacetylase 1 antibody, EC 3.-.-.-), Heparan sulfate N-sulfotransferase 1 antibody, EC 2.8.2.-)] antibody

UniProt: P52848

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Glycosaminoglycan Metabolic Process