BAAT Antikörper (AA 309-418)

Produktnummer ABIN7145588

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BAAT in WB, ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für BAAT Antikörper (AA 309-418) (ABIN7145588)

Target: BAAT (Bile Acid CoA: Amino Acid N-Acyltransferase (Glycine N-Choloyltransferase) (BAAT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAAT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-BAAT Antikörper

Bindungsspezifität: AA 309-418

Kreuzreaktivität: Human, Maus

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Bile acid-CoA:amino acid N-acyltransferase protein (309-418AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu BAAT

Target: BAAT (Bile Acid CoA: Amino Acid N-Acyltransferase (Glycine N-Choloyltransferase) (BAAT))

Andere Bezeichnung: BAAT

Hintergrund:

Background: Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids, or both. The conjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. In turn, bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs.

Aliases: FLJ20300 antibody, BAAT antibody, BAAT_HUMAN antibody, BACAT antibody, BAT antibody, Bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase) antibody, Bile acid CoA:amino acid N acyltransferase antibody, Bile acid Coenzyme A amino acid N acyltransferase glycine N choloyltransferase antibody, Bile acid Coenzyme A: amino acid N acyltransferase antibody, Bile acid-CoA:amino acid N-acyltransferase antibody, Glycine N choloyltransferase antibody, Glycine N-choloyltransferase antibody, Long chain fatty acyl CoA hydrolase antibody, Long-chain fatty-acyl-CoA hydrolase antibody, MGC104432 antibody

UniProt: Q14032