BRAP Antikörper (AA 13-124) (HRP)

Produktnummer ABIN7145761

Produktdetails anti-BRAP Antikörper (HRP)

Target: BRAP (BRCA1 Associated Protein (BRAP))

Bindungsspezifität: AA 13-124

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRAP Antikörper ist konjugiert mit HRP

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human BRCA1-associated protein (13-124AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu BRAP

Target: BRAP (BRCA1 Associated Protein (BRAP))

Andere Bezeichnung: BRAP (BRAP Produkte)

Synonyme: imp antikoerper, MGC68778 antikoerper, zgc:92894 antikoerper, BRAP antikoerper, BRAP2 antikoerper, IMP antikoerper, RNF52 antikoerper, 3010002G07Rik antikoerper, BRCA1 associated protein S homeolog antikoerper, BRCA1 associated protein antikoerper, BRCA1-associated protein antikoerper, brca1-associated protein antikoerper, brap.S antikoerper, brap antikoerper, BRAP antikoerper, NAEGRDRAFT_81654 antikoerper, CC1G_00971 antikoerper, CpipJ_CPIJ003557 antikoerper, Tsp_05101 antikoerper, LOC100282389 antikoerper, Brap antikoerper

Hintergrund:

Background: Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.

Aliases: BRAP antibody, RNF52BRCA1-associated protein antibody, EC 2.3.2.27 antibody, BRAP2 antibody, Impedes mitogenic signal propagation antibody, IMP antibody, RING finger protein 52 antibody, RING-type E3 ubiquitin transferase BRAP2 antibody, Renal carcinoma antigen NY-REN-63 antibody

UniProt: Q7Z569