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BRD7 Antikörper (AA 601-651) (Biotin)

BRD7 Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN7145817
  • Target Alle BRD7 Antikörper anzeigen
    BRD7 (Bromodomain Containing 7 (BRD7))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 601-651
    Reaktivität
    • 43
    • 34
    • 4
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 50
    • 1
    Kaninchen
    Klonalität
    • 49
    • 2
    Polyklonal
    Konjugat
    • 18
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BRD7 Antikörper ist konjugiert mit Biotin
    Applikation
    • 26
    • 20
    • 13
    • 13
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Bromodomain-containing protein 7 protein (601-651AA)
    Isotyp
    IgG
    Top Product
    Discover our top product BRD7 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    BRD7 (Bromodomain Containing 7 (BRD7))
    Andere Bezeichnung
    BRD7 (BRD7 Produkte)
    Synonyme
    zgc:66347 antikoerper, wu:fc95f02 antikoerper, MGC79478 antikoerper, BRD7 antikoerper, BP75 antikoerper, CELTIX1 antikoerper, NAG4 antikoerper, Ptpn13ip antikoerper, bromodomain containing 7 L homeolog antikoerper, bromodomain containing 7 antikoerper, brd7.L antikoerper, brd7 antikoerper, BRD7 antikoerper, Brd7 antikoerper
    Hintergrund

    Background: Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at \\\'Tyr-216\\\'. Down-regulates TRIM24-mediated activation of transcriptional activation by AR (By similarity). Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at \\\'Lys-9\\\' (H3K9ac). Binds to the ESR1 promoter. Recruits BRCA1 and POU2F1 to the ESR1 promoter. Coactivator for TP53-mediated activation of transcription of a set of target genes. Required for TP53-mediated cell-cycle arrest in response to oncogene activation. Promotes acetylation of TP53 at \\\'Lys-382\\\', and thereby promotes efficient recruitment of TP53 to target promoters. Inhibits cell cycle progression from G1 to S phase.

    Aliases: 75 kDa bromodomain protein antibody, BP75 antibody, BRD 7 antibody, BRD7 antibody, BRD7_HUMAN antibody, Bromodomain containing 7 antibody, bromodomain containing protein 7 antibody, Bromodomain-containing protein 7 antibody, CELTIX 1 antibody, CELTIX1 antibody, NAG4 antibody, Protein CELTIX-1 antibody

    UniProt
    Q9NPI1
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