CCDC109B Antikörper (Regulatory Subunit)

Produktnummer ABIN7146318

Produktdetails anti-CCDC109B Antikörper

Target: CCDC109B (Coiled-Coil Domain Containing 109B (CCDC109B))

Bindungsspezifität: AA 89-219, Regulatory Subunit

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCDC109B Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Calcium uniporter regulatory subunit MCUb, mitochondrial protein (89-219AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CCDC109B

Target: CCDC109B (Coiled-Coil Domain Containing 109B (CCDC109B))

Andere Bezeichnung: MCUB (CCDC109B Produkte)

Synonyme: 9030408N13Rik antikoerper, mitochondrial calcium uniporter dominant negative beta subunit antikoerper, MCUB antikoerper, Mcub antikoerper

Hintergrund:

Background: Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.

Aliases: MCUB antibody, CCDC109BCalcium uniporter regulatory subunit MCUb antibody, mitochondrial antibody, MCUb antibody, Coiled-coil domain-containing protein 109B antibody

UniProt: Q9NWR8