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SS18L1 Antikörper (AA 47-396)

SS18L1 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7146400
  • Target Alle SS18L1 Antikörper anzeigen
    SS18L1 (Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1))
    Bindungsspezifität
    • 7
    • 6
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 47-396
    Reaktivität
    • 27
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 26
    • 1
    Kaninchen
    Klonalität
    • 26
    • 1
    Polyklonal
    Konjugat
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    Dieser SS18L1 Antikörper ist unkonjugiert
    Applikation
    • 22
    • 18
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human, Maus
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Calcium-responsive transactivator protein (47-396AA)
    Isotyp
    IgG
  • Applikationshinweise
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    SS18L1 (Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1))
    Andere Bezeichnung
    SS18L1 (SS18L1 Produkte)
    Synonyme
    crest antikoerper, CREST antikoerper, LP2261 antikoerper, A230053O16Rik antikoerper, SS18L1, nBAF chromatin remodeling complex subunit antikoerper, synovial sarcoma translocation gene on chromosome 18-like 1 antikoerper, synovial sarcoma translocation gene on chromosome 18-like 1 S homeolog antikoerper, SS18, nBAF chromatin remodeling complex subunit like 1 antikoerper, SS18L1 antikoerper, ss18l1 antikoerper, ss18l1.S antikoerper, Ss18l1 antikoerper
    Hintergrund

    Background: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity).

    Aliases: Calcium-responsive transactivator antibody, CREST antibody, CREST_HUMAN antibody, KIAA0693 antibody, LP2261 antibody, MGC26711 antibody, MGC78386 antibody, sarcoma translocation gene on chromosome18like1 antibody, SS18 antibody, SS18-like protein 1 antibody, SS18L1 antibody, SS18L1 nBAF chromatin remodeling complex antibody, SSXT antibody, synovial sarcoma translocation antibody, synovial sarcoma translocation gene on chromosome 18-like 1 antibody, SYT homolog 1 antibody

    UniProt
    O75177
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