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COMP Antikörper (AA 20-160)

COMP Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7146850
  • Target Alle COMP Antikörper anzeigen
    COMP (Cartilage Oligomeric Matrix Protein (COMP))
    Bindungsspezifität
    • 15
    • 9
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-160
    Reaktivität
    • 56
    • 32
    • 25
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 70
    • 7
    • 1
    Kaninchen
    Klonalität
    • 72
    • 6
    Polyklonal
    Konjugat
    • 28
    • 12
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser COMP Antikörper ist unkonjugiert
    Applikation
    • 71
    • 24
    • 19
    • 19
    • 13
    • 9
    • 9
    • 6
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA
    Kreuzreaktivität
    Human, Maus
    Aufreinigung
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Cartilage oligomeric matrix protein (20-160AA)
    Isotyp
    IgG
    Top Product
    Discover our top product COMP Primärantikörper
  • Applikationshinweise
    Recommended dilution: WB:1:500-1:2000,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    COMP (Cartilage Oligomeric Matrix Protein (COMP))
    Andere Bezeichnung
    COMP (COMP Produkte)
    Synonyme
    COMP antikoerper, EDM1 antikoerper, EPD1 antikoerper, MED antikoerper, PSACH antikoerper, THBS5 antikoerper, TSP5 antikoerper, cartilage oligomeric matrix protein antikoerper, COMP antikoerper, sce3551 antikoerper, CJA_1292 antikoerper, Comp antikoerper
    Hintergrund

    Background: May play a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Could play a role in the pathogenesis of osteoarthritis. Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BIRC3, BIRC2, BIRC5 and XIAP). Essential for maintaining a vascular smooth muscle cells (VSMCs) contractile/differentiated phenotype under physiological and pathological stimuli. Maintains this phenotype of VSMCs by interacting with ITGA7.

    Aliases: cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple) antibody, Cartilage oligomeric matrix protein antibody, Cartilage oligomeric matrix protein precursor antibody, COMP antibody, COMP_HUMAN antibody, EDM 1 antibody, EDM1 antibody, EPD 1 antibody, EPD1 antibody, Epiphyseal dysplasia 1 antibody, Epiphyseal dysplasia 1 multiple antibody, Epiphyseal dysplasia multiple 1 antibody, MED antibody, MGC13181 antibody, MGC149768 antibody, PSACH antibody, pseudoachondroplasia (epiphyseal dysplasia 1, multiple) antibody, Pseudoachondroplasia antibody, THBS 5 antibody, THBS5 antibody, Thrombospondin 5 antibody, Thrombospondin-5 antibody, Thrombospondin5 antibody, TSP5 antibody

    UniProt
    P49747
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