CARD16 Antikörper (AA 1-197) (Biotin)

Produktnummer ABIN7146912

Produktdetails anti-CARD16 Antikörper (Biotin)

Target: CARD16 (Caspase Recruitment Domain Family, Member 16 (CARD16))

Bindungsspezifität: AA 1-197

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CARD16 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Caspase recruitment domain-containing protein 16 protein (1-197AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CARD16

Target: CARD16 (Caspase Recruitment Domain Family, Member 16 (CARD16))

Andere Bezeichnung: CARD16 (CARD16 Produkte)

Synonyme: COP antikoerper, COP1 antikoerper, PSEUDO-ICE antikoerper, caspase recruitment domain family member 16 antikoerper, CARD16 antikoerper

Hintergrund:

Background: Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.

Aliases: CAR16_HUMAN antibody, CARD only domain-containing protein 1 antibody, CARD only protein antibody, CARD16 antibody, Caspase recruitment domain family, member 16 antibody, Caspase recruitment domain-containing protein 16 antibody, Caspase-1 dominant-negative inhibitor pseudo-ICE antibody, Caspase-1 inhibitor COP antibody, COP antibody, COP1 antibody, Pseudo interleukin 1 beta converting enzyme antibody, Pseudo interleukin-1 beta converting enzyme antibody, Pseudo interleukin-1beta converting enzyme antibody, PSEUDO-ICE antibody

UniProt: Q5EG05