Caspase 1 Antikörper (AA 220-415) (Biotin)

Produktnummer ABIN7146934

Produktdetails anti-Caspase 1 Antikörper (Biotin)

Target: Caspase 1 (CASP1)

Bindungsspezifität: AA 220-415

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Caspase-10 protein (220-415AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Caspase 1

Target: Caspase 1 (CASP1)

Andere Bezeichnung: CASP1 (CASP1 Produkte)

Synonyme: ICE antikoerper, IL1BC antikoerper, P45 antikoerper, Il1bc antikoerper, Ice antikoerper, CASP1 antikoerper, CG5370 antikoerper, DCP-1 antikoerper, DCP1 antikoerper, Dcp1 antikoerper, Dmel\\CG5370 antikoerper, ccp1 antikoerper, dcp-1 antikoerper, dcp1 antikoerper, l(2)01862 antikoerper, l(2)02132 antikoerper, caspase 1 antikoerper, caspase 1, apoptosis-related cysteine peptidase antikoerper, caspase 4, apoptosis-related cysteine peptidase antikoerper, Death caspase-1 antikoerper, caspase-1 antikoerper, caspase antikoerper, caspase recruitment domain-containing protein 16 antikoerper, caspase 4 antikoerper, CASP1 antikoerper, Casp1 antikoerper, CASP4 antikoerper, Dcp-1 antikoerper, Caspase1 antikoerper, LOC5564196 antikoerper, LOC451519 antikoerper

Hintergrund:

Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC.

Aliases: ALPS2 antibody, Apoptotic protease Mch-4 antibody, CASP 10 antibody, CASP-10 antibody, CASP10 antibody, CASPA_HUMAN antibody, Caspase 10 apoptosis related cysteine peptidase antibody, Caspase-10 antibody, Caspase-10 subunit p12 antibody, FADD like ICE2 antibody, Fas associated death domain protein antibody, FAS-associated death domain protein interleukin-1B-converting enzyme 2 antibody, FLICE 2 antibody, FLICE2 antibody, ICE like apoptotic protease 4 antibody, ICE-like apoptotic protease 4 antibody, Interleukin 1B converting enzyme 2 antibody, MCH 4 antibody

UniProt: Q92851

Pathways: Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome