CTNNA1 Antikörper (AA 1-288)

Produktnummer ABIN7146972

Produktdetails anti-CTNNA1 Antikörper

Target: CTNNA1 (Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))

Bindungsspezifität: AA 1-288

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTNNA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Catenin alpha-1 protein (1-288AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:1000-1:2000, IF:1:200-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CTNNA1

Target: CTNNA1 (Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))

Andere Bezeichnung: CTNNA1 (CTNNA1 Produkte)

Synonyme: CAP102 antikoerper, 2010010M04Rik antikoerper, AA517462 antikoerper, AI988031 antikoerper, Catna1 antikoerper, CG17947 antikoerper, CT39986 antikoerper, Dalpha-Cat antikoerper, Dalpha-cat antikoerper, DalphaC antikoerper, Dalphacat antikoerper, Dmcatp antikoerper, Dmel\\CG17947 antikoerper, a-Cat antikoerper, a-cat antikoerper, alpha-CAT antikoerper, alpha-cat antikoerper, alpha-catenin antikoerper, alpha-ctn antikoerper, alphaCAT antikoerper, alphaCat antikoerper, alphacat antikoerper, Alpha-Cat antikoerper, dgri_GLEANR_3829 antikoerper, DgriGH19548 antikoerper, GH19548 antikoerper, ctnna antikoerper, cap102 antikoerper, catna1 antikoerper, ctnna1 antikoerper, catenin alpha 1 antikoerper, catenin (cadherin associated protein), alpha 1 antikoerper, alpha Catenin antikoerper, catenin alpha-1 antikoerper, catenin (cadherin-associated protein), alpha 1 antikoerper, catenin alpha 1 S homeolog antikoerper, CTNNA1 antikoerper, Ctnna1 antikoerper, alpha-Cat antikoerper, Dgri\alpha-Cat antikoerper, Tsp_10127 antikoerper, ctnna1 antikoerper, ctnna1.S antikoerper

Hintergrund:

Background: Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.

Aliases: Alpha E-catenin antibody, Cadherin associated protein 102 kDa antibody, Cadherin associated protein antibody, Cadherin-associated protein antibody, CAP 102 antibody, CAP102 antibody, Catenin (cadherin associated protein) alpha 1 102 kDa antibody, Catenin (cadherin associated protein), alpha 1, 102 kDa antibody, Catenin alpha 1 antibody, Catenin alpha-1 antibody, CTNA1_HUMAN antibody, CTNNA 1 antibody, Ctnna1 antibody, FLJ36832 antibody, FLJ52416 antibody, MDPT2 antibody, NY REN 13 antigen antibody, OTTHUMP00000224141 antibody, OTTHUMP00000224147 antibody, Renal carcinoma antigen NY REN 13 antibody, Renal carcinoma antigen NY-REN-13 antibody

UniProt: P35221

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location