CNOT3 Antikörper (AA 257-395)

Produktnummer ABIN7147101

Produktdetails anti-CNOT3 Antikörper

Target: CNOT3 (CCR4-NOT Transcription Complex, Subunit 3 (CNOT3))

Bindungsspezifität: AA 257-395

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CNOT3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human CCR4-NOT transcription complex subunit 3 protein (257-395AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CNOT3

Target: CNOT3 (CCR4-NOT Transcription Complex, Subunit 3 (CNOT3))

Andere Bezeichnung: CNOT3 (CNOT3 Produkte)

Synonyme: LENG2 antikoerper, NOT3 antikoerper, NOT3H antikoerper, A930039N10Rik antikoerper, cnot3 antikoerper, zgc:55934 antikoerper, wu:fi20g07 antikoerper, fb73b06 antikoerper, fc17h07 antikoerper, wu:fb73b06 antikoerper, wu:fc17h07 antikoerper, zgc:92813 antikoerper, CNOT3 antikoerper, Afu2g02070 antikoerper, AO090011000479 antikoerper, CG8426 antikoerper, Dmel\\CG8426 antikoerper, NOT3.5 antikoerper, NOT3/5 antikoerper, Not3 antikoerper, not3 antikoerper, not3/5 antikoerper, leng2 antikoerper, not3h antikoerper, CCR4-NOT transcription complex subunit 3 antikoerper, CCR4-NOT transcription complex, subunit 3 antikoerper, CCR4-NOT transcription complex, subunit 3b antikoerper, CCR4-NOT transcription complex, subunit 3a antikoerper, CCR4-NOT transcription complex subunit 3 S homeolog antikoerper, CNOT3 antikoerper, Cnot3 antikoerper, cnot3b antikoerper, cnot3a antikoerper, AFUA_2G02070 antikoerper, NFIA_034440 antikoerper, ACLA_092760 antikoerper, PMAA_089540 antikoerper, AFLA_043060 antikoerper, TSTA_125290 antikoerper, ANI_1_738064 antikoerper, AOR_1_812054 antikoerper, Not3 antikoerper, cnot3 antikoerper, cnot3.S antikoerper

Hintergrund:

Background: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regulation, may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation, the repressive function may involve histone deacetylases. Involved in the maintenance of emryonic stem (ES) cell identity.

Aliases: CCR4 associated factor 3 antibody, CCR4-associated factor 3 antibody, CCR4-NOT transcription complex subunit 3 antibody, CNOT3 antibody, CNOT3_HUMAN antibody, KIAA0691 antibody, LENG2 antibody, Leukocyte receptor cluster member 2 antibody, negative regulator of transcription 3, S. cerevisiae, homolog of antibody, NOT3 (negative regulator of transcription 3, yeast) homolog antibody, NOT3 antibody, NOT3H antibody

UniProt: O75175

Pathways: Stem Cell Maintenance