CD166 Antikörper (AA 28-516)

Produktnummer ABIN7147124

Produktdetails anti-CD166 Antikörper

Target: CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))

Bindungsspezifität: AA 28-516

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD166 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human CD166 antigen protein (28-516AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CD166

Target: CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))

Andere Bezeichnung: ALCAM (ALCAM Produkte)

Synonyme: CD166 antikoerper, MEMD antikoerper, ALCAM antikoerper, BEN antikoerper, DM-GRASP antikoerper, JC7 antikoerper, SC1 antikoerper, AI853494 antikoerper, MuSC antikoerper, alcam antikoerper, cd166 antikoerper, memd antikoerper, fb53h09 antikoerper, fb80a10 antikoerper, nlcam antikoerper, si:ch211-190h2.4 antikoerper, wu:fb53h09 antikoerper, wu:fb80a10 antikoerper, wu:fc14b01 antikoerper, activated leukocyte cell adhesion molecule antikoerper, activated leukocyte cell adhesion molecule a antikoerper, activated leukocyte cell adhesion molecule L homeolog antikoerper, CD166 antigen homolog antikoerper, activated leukocyte cell adhesion molecule b antikoerper, ALCAM antikoerper, Alcam antikoerper, alcama antikoerper, alcam.L antikoerper, alcam antikoerper, cd166 antikoerper, alcamb antikoerper

Hintergrund:

Background: Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts (PubMed:7760007, PubMed:15496415, PubMed:15048703, PubMed:16352806, PubMed:23169771, PubMed:24945728). Promotes T-cell activation and proliferation via its interactions with CD6 (PubMed:15048703, PubMed:16352806, PubMed:24945728). Contributes to the formation and maturation of the immunological synapse via its interactions with CD6 (PubMed:15294938, PubMed:16352806). Mediates homotypic interactions with cells that express ALCAM (PubMed:15496415, PubMed:16352806). Required for normal hematopoietic stem cell engraftment in the bone marrow (PubMed:24740813). Mediates attachment of dendritic cells onto endothelial cells via homotypic interaction (PubMed:23169771). Inhibits endothelial cell migration and promotes endothelial tube formation via homotypic interactions (PubMed:15496415, PubMed:23169771). Required for normal organization of the lymph vessel network. Required for normal hematopoietic stem cell engraftment in the bone marrow. Plays a role in hematopoiesis, required for normal numbers of hematopoietic stem cells in bone marrow. Promotes in vitro osteoblast proliferation and differentiation (By similarity). Promotes neurite extension, axon growth and axon guidance, axons grow preferentially on surfaces that contain ALCAM. Mediates outgrowth and pathfinding for retinal ganglion cell axons (By similarity).

Aliases: Activated leukocyte cell adhesion molecule antibody, ALCAM antibody, ALCAM protein antibody, CD 166 antibody, CD166 antibody, CD166 antigen antibody, CD166_HUMAN antibody, FLJ3851 antibody, FLJ38514 antibody, MEMD antibody, MGC71733 antibody

UniProt: Q13740