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CD31 Antikörper (AA 28-315)

PECAM1 Reaktivität: Human FACS, WB, IHC, IF, ELISA Wirt: Maus Monoclonal 9E6E12 unconjugated
Produktnummer ABIN7147154
  • Target Alle CD31 (PECAM1) Antikörper anzeigen
    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
    Bindungsspezifität
    • 16
    • 16
    • 16
    • 12
    • 8
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 28-315
    Reaktivität
    • 268
    • 145
    • 72
    • 59
    • 42
    • 28
    • 21
    • 18
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 155
    • 146
    • 53
    • 6
    • 3
    • 2
    Maus
    Klonalität
    • 233
    • 131
    • 1
    Monoklonal
    Konjugat
    • 158
    • 32
    • 31
    • 25
    • 13
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD31 Antikörper ist unkonjugiert
    Applikation
    • 228
    • 184
    • 98
    • 98
    • 62
    • 40
    • 36
    • 33
    • 26
    • 26
    • 19
    • 15
    • 13
    • 9
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    Protein G purified
    Immunogen
    Recombinant Human CD31 protein (28-315AA)
    Klon
    9E6E12
    Isotyp
    IgG2a
    Top Product
    Discover our top product PECAM1 Primärantikörper
  • Applikationshinweise
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:500, IF:1:50-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
    Andere Bezeichnung
    CD31 (PECAM1 Produkte)
    Synonyme
    CD31 antikoerper, CD31/EndoCAM antikoerper, GPIIA' antikoerper, PECA1 antikoerper, PECAM-1 antikoerper, endoCAM antikoerper, C85791 antikoerper, Cd31 antikoerper, Pecam antikoerper, platelet/endothelial cell adhesion molecule 1 antikoerper, platelet and endothelial cell adhesion molecule 1 antikoerper, pecam1 antikoerper, PECAM1 antikoerper, Pecam1 antikoerper
    Hintergrund

    Background: Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions (PubMed:19342684, PubMed:17580308). Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes (PubMed:19342684). Heterophilic interaction with CD177 plays a role in transendothelial migration of neutrophils (PubMed:17580308). Homophilic ligation of PECAM1 prevents macrophage-mediated phagocytosis of neighboring viable leukocytes by transmitting a detachment signal (PubMed:12110892). Promotes macrophage-mediated phagocytosis of apoptotic leukocytes by tethering them to the phagocytic cells, PECAM1-mediated detachment signal appears to be disabled in apoptotic leukocytes (PubMed:12110892). Modulates bradykinin receptor BDKRB2 activation (PubMed:18672896). Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in endothelial cells (PubMed:18672896). Induces susceptibility to atherosclerosis (By similarity).

    Aliases: Platelet endothelial cell adhesion molecule, PECAM-1, EndoCAM, GPIIA', PECA1, CD31, PECAM1

    UniProt
    P16284
    Pathways
    Regulation of Actin Filament Polymerization
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