CDK5RAP3 Antikörper (Regulatory Subunit) (FITC)
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- Target Alle CDK5RAP3 Antikörper anzeigen
- CDK5RAP3 (CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3))
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Bindungsspezifität
- AA 42-292, Regulatory Subunit
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CDK5RAP3 Antikörper ist konjugiert mit FITC
- Applikation
- Bitte anfragen
- Kreuzreaktivität
- Human
- Aufreinigung
- Antigen Affinity Purified
- Immunogen
- Recombinant Human CDK5 regulatory subunit-associated protein 3 protein (42-292AA)
- Isotyp
- IgG
- Top Product
- Discover our top product CDK5RAP3 Primärantikörper
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- CDK5RAP3 (CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3))
- Andere Bezeichnung
- CDK5RAP3 (CDK5RAP3 Produkte)
- Synonyme
- cdkrap3 antikoerper, fb33h04 antikoerper, fc09c05 antikoerper, id:ibd2920 antikoerper, wu:fb33h04 antikoerper, wu:fc09c05 antikoerper, zgc:86863 antikoerper, CDK5RAP3 antikoerper, cdk5rap3 antikoerper, MGC82350 antikoerper, C53 antikoerper, HSF-27 antikoerper, IC53 antikoerper, LZAP antikoerper, MST016 antikoerper, OK/SW-cl.114 antikoerper, PP1553 antikoerper, 1810007E24Rik antikoerper, BC002318 antikoerper, C81486 antikoerper, CDK5 regulatory subunit associated protein 3 antikoerper, CDK5 regulatory subunit associated protein 3 L homeolog antikoerper, cdk5rap3 antikoerper, CDK5RAP3 antikoerper, cdk5rap3.L antikoerper, Cdk5rap3 antikoerper
- Hintergrund
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Background: Probable tumor suppressor initially identified as a CDK5R1 interactor controlling cell proliferation (PubMed:12054757, PubMed:12737517). Negatively regulates NF-kappa-B-mediated gene transcription through the control of RELA phosphorylation (PubMed:17785205, PubMed:20228063). Also regulates mitotic G2/M transition checkpoint and mitotic G2 DNA damage checkpoint (PubMed:15790566, PubMed:19223857). Through its interaction with CDKN2A/ARF and MDM2 may induce MDM2-dependent p53/TP53 ubiquitination, stabilization and activation in the nucleus, thereby promoting G1 cell cycle arrest and inhibition of cell proliferation (PubMed:16173922). May play a role in the unfolded protein response, mediating the ufmylation of multiple proteins in response to endoplasmic reticulum stress (PubMed:23152784). May also play a role in the rupture of the nuclear envelope during apoptosis (PubMed:23478299). May regulate MAPK14 activity by regulating its dephosphorylation by PPM1D/WIP1 (PubMed:21283629).
Aliases: C53 antibody, CDK5 activator binding protein C53 antibody, CDK5 activator-binding protein C53 antibody, CDK5 regulatory subunit associated protein 3 antibody, CDK5 regulatory subunit-associated protein 3 antibody, Cdk5rap3 antibody, CK5P3_HUMAN antibody, HSF 27 antibody, HSF27 antibody, IC53 antibody, Ischemic heart CDK5 activator binding protein C53 antibody, LXXLL/leucine zipper containing ARFbinding protein antibody, LZAP antibody, MST016 antibody, OK/SW cl.114 antibody, PP1553 antibody, Protein HSF-27 antibody
- UniProt
- Q96JB5
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