CCAR1 Antikörper (AA 1-200)

Produktnummer ABIN7147295

Produktdetails anti-CCAR1 Antikörper

Target: CCAR1 (Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))

Bindungsspezifität: AA 1-200

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCAR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Cell division cycle and apoptosis regulator protein 1 protein (1-200AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CCAR1

Target: CCAR1 (Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))

Andere Bezeichnung: CCAR1 (CCAR1 Produkte)

Hintergrund:

Background: Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation (By similarity). May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation.

Aliases: CARP-1 antibody, Carp1 antibody, Ccar1 antibody, CCAR1_HUMAN antibody, Cell cycle and apoptosis regulatory protein 1 antibody, cell division cycle and apoptosis regulator 1 antibody, Cell division cycle and apoptosis regulator protein 1 antibody, Death inducer with SAP domain antibody, FLJ10590 antibody, FLJ10839 antibody, FLJ13376 antibody, FLJ20734 antibody, MGC7730 antibody, RP11-437A18.1 antibody

UniProt: Q8IX12