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MCAM Antikörper (AA 50-646)

MCAM Reaktivität: Human FACS, WB, IF, ELISA Wirt: Maus Monoclonal 4D10C7 unconjugated
Produktnummer ABIN7147325
  • Target Alle MCAM Antikörper anzeigen
    MCAM (Melanoma Cell Adhesion Molecule (MCAM))
    Bindungsspezifität
    • 16
    • 13
    • 11
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 50-646
    Reaktivität
    • 134
    • 53
    • 47
    • 14
    • 14
    • 9
    • 8
    • 7
    • 6
    • 2
    Human
    Wirt
    • 96
    • 62
    • 8
    • 1
    • 1
    Maus
    Klonalität
    • 89
    • 79
    Monoklonal
    Konjugat
    • 71
    • 14
    • 14
    • 11
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MCAM Antikörper ist unkonjugiert
    Applikation
    • 86
    • 79
    • 70
    • 43
    • 21
    • 20
    • 14
    • 10
    • 10
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    Protein G purified
    Immunogen
    Recombinant Human Cell surface glycoprotein MUC18 protein (50-646AA)
    Klon
    4D10C7
    Isotyp
    IgG2a
    Top Product
    Discover our top product MCAM Primärantikörper
  • Applikationshinweise
    Recommended dilution: WB:1:500-1:2000, IF:1:50-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    MCAM (Melanoma Cell Adhesion Molecule (MCAM))
    Andere Bezeichnung
    CD146 (MCAM Produkte)
    Synonyme
    CD146 antikoerper, MUC18 antikoerper, Muc18 antikoerper, 1-gicerin antikoerper, AV025631 antikoerper, CD149 antikoerper, s-endo antikoerper, s-gicerin antikoerper, cd146 antikoerper, gicerin antikoerper, id:ibd3512 antikoerper, mcam antikoerper, MCAM antikoerper, melanoma cell adhesion molecule antikoerper, melanoma cell adhesion molecule b antikoerper, MCAM antikoerper, Mcam antikoerper, mcamb antikoerper
    Hintergrund

    Background: Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

    Aliases: Cell surface glycoprotein MUC18 (Cell surface glycoprotein P1H12) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (Melanoma-associated antigen MUC18) (S-endo 1 endothelial-associated antigen) (CD antigen CD146), MCAM, MUC18

    UniProt
    P43121
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