CCM2 Antikörper (AA 1-300)

Produktnummer ABIN7147492

Produktdetails anti-CCM2 Antikörper

Target: CCM2 (Cerebral Cavernous Malformation 2 (CCM2))

Bindungsspezifität: AA 1-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCM2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Cerebral cavernous malformations 2 protein (1-300AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CCM2

Target: CCM2 (Cerebral Cavernous Malformation 2 (CCM2))

Andere Bezeichnung: CCM2 (CCM2 Produkte)

Synonyme: C7orf22 antikoerper, OSM antikoerper, malcavernin antikoerper, CCM2 antikoerper, BC029157 antikoerper, TUF2 antikoerper, vtn antikoerper, zgc:110233 antikoerper, CCM2 scaffolding protein antikoerper, cerebral cavernous malformation 2 antikoerper, malcavernin antikoerper, CCM2 antikoerper, Ccm2 antikoerper, LOC100304744 antikoerper, ccm2 antikoerper

Hintergrund:

Background: Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions (By similarity). May function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock (By similarity).

Aliases: C7orf22 antibody, Ccm2 antibody, CCM2 gene antibody, CCM2_HUMAN antibody, Cerebral cavernous malformation 2 antibody, Cerebral cavernous malformations 2 protein antibody, Chromosome 7 open reading frame 22 antibody, Malcavernin antibody, MGC4067 antibody, MGC4607 antibody, MGC74868 antibody, OSM antibody, Osmosensing scaffold for MEKK3 antibody, OTTHUMP00000159554 antibody, OTTHUMP00000214270 antibody, OTTHUMP00000214271 antibody, OTTHUMP00000214273 antibody, PP10187 antibody

UniProt: Q9BSQ5

Pathways: Cell-Cell Junction Organization