CLN5 Antikörper (AA 42-181)

Produktnummer ABIN7147493

Produktdetails anti-CLN5 Antikörper

Target: CLN5 (Ceroid-Lipofuscinosis, Neuronal 5 (CLN5))

Bindungsspezifität: AA 42-181

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLN5 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Ceroid-lipofuscinosis neuronal protein 5 protein (42-181AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CLN5

Target: CLN5 (Ceroid-Lipofuscinosis, Neuronal 5 (CLN5))

Andere Bezeichnung: CLN5 (CLN5 Produkte)

Synonyme: NCL antikoerper, A730075N08Rik antikoerper, CLN5, intracellular trafficking protein antikoerper, ceroid-lipofuscinosis, neuronal 5 antikoerper, CLN5 antikoerper, Cln5 antikoerper

Hintergrund:

Background: Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane (PubMed:22431521).

Aliases: Ceroid lipofuscinosis neuronal 5 antibody, Ceroid-lipofuscinosis neuronal protein 5 antibody, CLN5 antibody, CLN5_HUMAN antibody, NCL antibody, Protein CLN5 antibody

UniProt: O75503