CHMP1B Antikörper (AA 1-199)

Produktnummer ABIN7147518

Produktdetails anti-CHMP1B Antikörper

Target: CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))

Bindungsspezifität: AA 1-199

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHMP1B Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Charged multivesicular body protein 1b protein (1-199AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CHMP1B

Target: CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))

Andere Bezeichnung: CHMP1B (CHMP1B Produkte)

Synonyme: C10orf2 antikoerper, C18-ORF2 antikoerper, C18orf2 antikoerper, CHMP1.5 antikoerper, Vps46-2 antikoerper, Vps46B antikoerper, hVps46-2 antikoerper, 2810405I11Rik antikoerper, Chmp1b1 antikoerper, Chmp1.5 antikoerper, fb10c03 antikoerper, wu:fb10c03 antikoerper, zgc:56134 antikoerper, chromatin modifying protein 1b antikoerper, hypothetical protein antikoerper, charged multivesicular body protein 1B antikoerper, chromatin modifying protein 1B antikoerper, LOC692931 antikoerper, PGTG_18215 antikoerper, CHMP1B antikoerper, Chmp1b antikoerper, chmp1b antikoerper

Hintergrund:

Background: Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in cytokinesis. Involved in recruiting VPS4A and/or VPS4B and SPAST to the midbody of dividing cells. Involved in HIV-1 p6- and p9-dependent virus release.

Aliases: CHMP1B antibody, C18orf2Charged multivesicular body protein 1b antibody, CHMP1.5 antibody, Chromatin-modifying protein 1b antibody, CHMP1b antibody, Vacuolar protein sorting-associated protein 46-2 antibody, Vps46-2 antibody, hVps46-2 antibody

UniProt: Q7LBR1