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CHMP6 Antikörper (AA 2-201)

CHMP6 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7147533
  • Target Alle CHMP6 Antikörper anzeigen
    CHMP6 (Charged Multivesicular Body Protein 6 (CHMP6))
    Bindungsspezifität
    • 14
    • 8
    • 5
    • 4
    • 1
    • 1
    • 1
    AA 2-201
    Reaktivität
    • 27
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 29
    • 2
    Kaninchen
    Klonalität
    • 31
    Polyklonal
    Konjugat
    • 17
    • 4
    • 3
    • 3
    • 2
    • 2
    Dieser CHMP6 Antikörper ist unkonjugiert
    Applikation
    • 27
    • 18
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human, Ratte
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Charged multivesicular body protein 6 protein (2-201AA)
    Isotyp
    IgG
  • Applikationshinweise
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    CHMP6 (Charged Multivesicular Body Protein 6 (CHMP6))
    Andere Bezeichnung
    CHMP6 (CHMP6 Produkte)
    Synonyme
    chmp6 antikoerper, vps20 antikoerper, 2400004G01Rik antikoerper, VPS20 antikoerper, RGD1565325 antikoerper, chmp6l antikoerper, flj11749l antikoerper, wu:fb79d02 antikoerper, zgc:110067 antikoerper, charged multivesicular body protein 6 antikoerper, charged multivesicular body protein 6 L homeolog antikoerper, charged multivesicular body protein 6 S homeolog antikoerper, charged multivesicular body protein 6b antikoerper, LOC100280982 antikoerper, chmp6.L antikoerper, chmp6.S antikoerper, CHMP6 antikoerper, chmp6 antikoerper, Tsp_08316 antikoerper, Chmp6 antikoerper, chmp6b antikoerper
    Hintergrund

    Background: Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. In the ESCRT-III complex, it probably serves as an acceptor for the ESCRT-II complex on endosomal membranes.

    Aliases: Charged multivesicular body protein 6 antibody, chmp6 antibody, CHMP6_HUMAN antibody, Chromatin modifying protein 6 antibody, Chromatin-modifying protein 6 antibody, FLJ11749 antibody, hVps 20 antibody, hVps20 antibody, novel SNF7 protein antibody, OTTMUSP00000004363 antibody, RGD1565325 antibody, RP24 225K18.4 antibody, Vacuolar protein sorting associated protein 20 antibody, Vacuolar protein sorting-associated protein 20 antibody, Vps 20 antibody, Vps20 antibody

    UniProt
    Q96FZ7
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