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HUS1 Antikörper (AA 2-280)

HUS1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7147541
  • Target Alle HUS1 Antikörper anzeigen
    HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 7
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-280
    Reaktivität
    • 51
    • 28
    • 15
    Human
    Wirt
    • 62
    • 4
    Kaninchen
    Klonalität
    • 65
    • 1
    Polyklonal
    Konjugat
    • 23
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HUS1 Antikörper ist unkonjugiert
    Applikation
    • 31
    • 26
    • 13
    • 13
    • 9
    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Checkpoint protein HUS1 protein (2-280AA)
    Isotyp
    IgG
    Top Product
    Discover our top product HUS1 Primärantikörper
  • Applikationshinweise
    Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
    Andere Bezeichnung
    HUS1 (HUS1 Produkte)
    Synonyme
    hHUS1 antikoerper, mHus1 antikoerper, XHus1 antikoerper, hus1 antikoerper, HUS1 checkpoint clamp component antikoerper, checkpoint clamp complex protein Hus1 antikoerper, HUS1 checkpoint clamp component L homeolog antikoerper, HUS1 antikoerper, Hus1 antikoerper, hus1 antikoerper, hus1.L antikoerper
    Hintergrund

    Background: Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3\\\'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds, endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths, and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase.

    Aliases: Checkpoint protein HUS1 antibody, hHUS1 antibody, HUS1 (S. pombe) checkpoint homolog antibody, Hus1 antibody, HUS1 checkpoint homolog (S. pombe) antibody, HUS1 Checkpoint Protein antibody, HUS1 protein antibody, HUS1+ - like protein antibody, HUS1_HUMAN antibody, Hydroxyurea-sensitive 1, S. pombe, homolog of antibody

    UniProt
    O60921
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