CH25H Antikörper (AA 142-272)

Produktnummer ABIN7147600

Produktdetails anti-CH25H Antikörper

Target: CH25H (Cholesterol 25-Hydroxylase (CH25H))

Bindungsspezifität: AA 142-272

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CH25H Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Cholesterol 25-hydroxylase protein (142-272AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CH25H

Target: CH25H (Cholesterol 25-Hydroxylase (CH25H))

Andere Bezeichnung: CH25H (CH25H Produkte)

Synonyme: CH25H antikoerper, zgc:101688 antikoerper, MGC143045 antikoerper, C25H antikoerper, AI462618 antikoerper, m25OH antikoerper, cholesterol 25-hydroxylase antikoerper, cholesterol 25-hydroxylase L homeolog antikoerper, CH25H antikoerper, ch25h antikoerper, Ch25h antikoerper, ch25h.L antikoerper

Hintergrund:

Background: Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes (PubMed:9852097). Plays a key role in cell positioning and movement in lymphoid tissues: 25-hydroxycholesterol is an intermediate in biosynthesis of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC), an oxysterol that acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation.

Aliases: CH25H antibody, Cholesterol 25-hydroxylase antibody, EC 1.14.99.38 antibody, Cholesterol 25-monooxygenase antibody, h25OH antibody

UniProt: O95992