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BHLHE41 Antikörper (AA 185-285) (HRP)

BHLHE41 Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN7147844
  • Target Alle BHLHE41 Antikörper anzeigen
    BHLHE41 (Basic Helix-Loop-Helix Family, Member E41 (BHLHE41))
    Bindungsspezifität
    • 7
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 185-285
    Reaktivität
    • 40
    • 22
    • 15
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 31
    • 8
    • 1
    Kaninchen
    Klonalität
    • 33
    • 7
    Polyklonal
    Konjugat
    • 25
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BHLHE41 Antikörper ist konjugiert mit HRP
    Applikation
    • 30
    • 19
    • 7
    • 5
    • 4
    • 4
    • 1
    • 1
    ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Class E basic helix-loop-helix protein 41 protein (185-285AA)
    Isotyp
    IgG
    Top Product
    Discover our top product BHLHE41 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    BHLHE41 (Basic Helix-Loop-Helix Family, Member E41 (BHLHE41))
    Andere Bezeichnung
    BHLHE41 (BHLHE41 Produkte)
    Synonyme
    BHLHB3 antikoerper, dec2 antikoerper, bhlhb3 antikoerper, sharp1 antikoerper, sharp-1 antikoerper, MGC108143 antikoerper, DEC2 antikoerper, SHARP1 antikoerper, hDEC2 antikoerper, 6430520M22Rik antikoerper, Bhlhb2l antikoerper, Bhlhb3 antikoerper, Sharp1 antikoerper, Dec2 antikoerper, SHARP-1 antikoerper, basic helix-loop-helix family member e41 antikoerper, basic helix-loop-helix family, member e41 antikoerper, BHLHE41 antikoerper, bhlhe41 antikoerper, Bhlhe41 antikoerper
    Hintergrund

    Background: Transcriptional repressor involved in the regulation of the circadian rhythm by negatively regulating the activity of the clock genes and clock-controlled genes. Acts as the negative limb of a novel autoregulatory feedback loop (DEC loop) which differs from the one formed by the PER and CRY transcriptional repressors (PER/CRY loop). Both these loops are interlocked as it represses the expression of PER1 and in turn is repressed by PER1/2 and CRY1/2. Represses the activity of the circadian transcriptional activator: CLOCK-ARNTL/BMAL1 heterodimer by competing for the binding to E-box elements (5\'-CACGTG-3\') found within the promoters of its target genes. Negatively regulates its own expression and the expression of DBP and BHLHE41/DEC2. Acts as a corepressor of RXR and the RXR-LXR heterodimers and represses the ligand-induced RXRA/B/G, NR1H3/LXRA, NR1H4 and VDR transactivation activity.

    Aliases: Basic helix-loop-helix domain containing class B3 antibody, BHE41_HUMAN antibody, bHLH protein DEC2 antibody, bHLHB3 antibody, bHLHe41 antibody, Class B basic helix loop helix protein 3 antibody, Class B basic helix-loop-helix protein 3 antibody, Class E basic helix-loop-helix protein 41 antibody, DEC2 antibody, Differentially expressed in chondrocytes protein 2 antibody, Enhancer of split and hairy related protein 1 antibody, Enhancer-of-split and hairy-related protein 1 antibody, hDEC2 antibody, Moderately similar to basic-helix loop helix protein M.musculus antibody, SHARP-1 antibody

    UniProt
    Q9C0J9
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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