BHLHE41 Antikörper (AA 185-285) (HRP)
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- Target Alle BHLHE41 Antikörper anzeigen
- BHLHE41 (Basic Helix-Loop-Helix Family, Member E41 (BHLHE41))
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Bindungsspezifität
- AA 185-285
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser BHLHE41 Antikörper ist konjugiert mit HRP
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Applikation
- ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Class E basic helix-loop-helix protein 41 protein (185-285AA)
- Isotyp
- IgG
- Top Product
- Discover our top product BHLHE41 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- BHLHE41 (Basic Helix-Loop-Helix Family, Member E41 (BHLHE41))
- Andere Bezeichnung
- BHLHE41 (BHLHE41 Produkte)
- Synonyme
- BHLHB3 antikoerper, dec2 antikoerper, bhlhb3 antikoerper, sharp1 antikoerper, sharp-1 antikoerper, MGC108143 antikoerper, DEC2 antikoerper, SHARP1 antikoerper, hDEC2 antikoerper, 6430520M22Rik antikoerper, Bhlhb2l antikoerper, Bhlhb3 antikoerper, Sharp1 antikoerper, Dec2 antikoerper, SHARP-1 antikoerper, basic helix-loop-helix family member e41 antikoerper, basic helix-loop-helix family, member e41 antikoerper, BHLHE41 antikoerper, bhlhe41 antikoerper, Bhlhe41 antikoerper
- Hintergrund
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Background: Transcriptional repressor involved in the regulation of the circadian rhythm by negatively regulating the activity of the clock genes and clock-controlled genes. Acts as the negative limb of a novel autoregulatory feedback loop (DEC loop) which differs from the one formed by the PER and CRY transcriptional repressors (PER/CRY loop). Both these loops are interlocked as it represses the expression of PER1 and in turn is repressed by PER1/2 and CRY1/2. Represses the activity of the circadian transcriptional activator: CLOCK-ARNTL/BMAL1 heterodimer by competing for the binding to E-box elements (5\'-CACGTG-3\') found within the promoters of its target genes. Negatively regulates its own expression and the expression of DBP and BHLHE41/DEC2. Acts as a corepressor of RXR and the RXR-LXR heterodimers and represses the ligand-induced RXRA/B/G, NR1H3/LXRA, NR1H4 and VDR transactivation activity.
Aliases: Basic helix-loop-helix domain containing class B3 antibody, BHE41_HUMAN antibody, bHLH protein DEC2 antibody, bHLHB3 antibody, bHLHe41 antibody, Class B basic helix loop helix protein 3 antibody, Class B basic helix-loop-helix protein 3 antibody, Class E basic helix-loop-helix protein 41 antibody, DEC2 antibody, Differentially expressed in chondrocytes protein 2 antibody, Enhancer of split and hairy related protein 1 antibody, Enhancer-of-split and hairy-related protein 1 antibody, hDEC2 antibody, Moderately similar to basic-helix loop helix protein M.musculus antibody, SHARP-1 antibody
- UniProt
- Q9C0J9
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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