CLASP1 Antikörper (AA 1389-1538)

Produktnummer ABIN7147935

Produktdetails anti-CLASP1 Antikörper

Target: CLASP1 (Cytoplasmic Linker Associated Protein 1 (CLASP1))

Bindungsspezifität: AA 1389-1538

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLASP1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human CLIP-associating protein 1 protein (1389-1538AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CLASP1

Target: CLASP1 (Cytoplasmic Linker Associated Protein 1 (CLASP1))

Andere Bezeichnung: CLASP1 (CLASP1 Produkte)

Hintergrund:

Background: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.

Aliases: 1700030C23Rik antibody, 5730583A19Rik antibody, B130045P17Rik antibody, CLAP1_HUMAN antibody, clasp1 antibody, CLIP associating protein 1 antibody, CLIP associating protein CLASP1 antibody, CLIP-associating protein 1 antibody, Cytoplasmic linker associated protein 1 antibody, Cytoplasmic linker-associated protein 1 antibody, DKFZp686D1968 antibody, DKFZp686H2039 antibody, FLJ33821 antibody, FLJ41222 antibody, hOrbit1 antibody, KIAA0622 antibody, MAST1 antibody, MGC131895 antibody, mKIAA0622 antibody, Multiple asters 1 antibody, Multiple asters homolog 1 antibody, Protein Orbit homolog 1 antibody

UniProt: Q7Z460

Pathways: Microtubule Dynamics, M Phase, Maintenance of Protein Location