C4B Antikörper (AA 1454-1744)
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- Target Alle C4B (C4b) Antikörper anzeigen
- C4B (C4b) (Complement Component C4b (C4b))
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Bindungsspezifität
- AA 1454-1744
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser C4B Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Complement C4-B protein (1454-1744AA)
- Isotyp
- IgG
- Top Product
- Discover our top product C4b Primärantikörper
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anti-Complement Component C4b (C4b) (AA 126-366) antibody
C4b Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Complement Component C4b (C4b) (AA 680-756) antibodyC4b Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Complement Component C4b (C4b) (AA 1347-1446) antibodyC4b Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 1F2 unconjugated
anti-Complement Component C4b (C4b) (AA 19-333) antibodyC4b Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Complement Component C4b (C4b) (AA 655-684) antibodyC4b Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB33642 unconjugated
anti-Complement Component C4b (C4b) antibodyC4b Reaktivität: Human IHC, IF, StM Wirt: Maus Monoclonal SPM545 unconjugated
anti-Complement Component C4b (C4b) (AA 144-193) antibodyC4b Reaktivität: Human, Maus, Pferd, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-Complement Component C4b (C4b) (AA 655-684) antibodyC4b Reaktivität: Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- C4B (C4b) (Complement Component C4b (C4b))
- Andere Bezeichnung
- C4B (C4b Produkte)
- Hintergrund
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Background: Non-enzymatic component of the C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens. Ref.16 Ref.17 Derived from proteolytic degradation of complement C4, C4a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
Aliases: Basic complement C4 antibody, C2B5 antibody, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3 antibody, C4b antibody, C4B1 antibody, C4B2 antibody, C4B3 antibody, CO4B_HUMAN antibody, Complement C4 gamma chain antibody, Complement component 4B antibody, CPAMD3 antibody
- UniProt
- P0C0L5
- Pathways
- Komplementsystem
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