COPS8 Antikörper (AA 150-198) (HRP)
-
- Target Alle COPS8 Antikörper anzeigen
- COPS8 (COP9 Signalosome Subunit 8 (COPS8))
-
Bindungsspezifität
- AA 150-198
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser COPS8 Antikörper ist konjugiert mit HRP
-
Applikation
- ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human COP9 signalosome complex subunit 8 protein (150-198AA)
- Isotyp
- IgG
- Top Product
- Discover our top product COPS8 Primärantikörper
-
anti-COP9 Signalosome Subunit 8 (COPS8) (AA 1-209) antibody
COPS8 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (AA 1-209) antibodyCOPS8 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (AA 1-209) antibodyCOPS8 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (C-Term) antibodyCOPS8 Reaktivität: Human, Ratte, Maus WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (Middle Region) antibodyCOPS8 Reaktivität: Human, Ratte, Maus, Pferd, Kaninchen, Rind (Kuh), Meerschweinchen, Hund WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (AA 1-209) antibodyCOPS8 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2G8 unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (AA 150-198) antibodyCOPS8 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (Internal Region) antibodyCOPS8 Reaktivität: Human, Ratte, Maus WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Signalosome Subunit 8 (COPS8) (C-Term) antibodyCOPS8 Reaktivität: Human, Ratte, Maus, Pferd, Kaninchen, Rind (Kuh), Meerschweinchen, Hamster, Affe WB Wirt: Kaninchen Polyclonal unconjugated
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Target
- COPS8 (COP9 Signalosome Subunit 8 (COPS8))
- Andere Bezeichnung
- COPS8 (COPS8 Produkte)
- Hintergrund
-
Background: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
Aliases: COP9 homolog antibody, COP9 signalosome complex subunit 8 antibody, COP9 signalosome subunit 8 antibody, Cops8 antibody, CSN8 antibody, CSN8_HUMAN antibody, hCOP9 antibody, JAB1 containing signalosome subunit 8 antibody, JAB1-containing signalosome subunit 8 antibody, SGN8 antibody, Signalosome subunit 8 antibody
- UniProt
- Q99627
- Pathways
- Zellzyklus
-
