Coxsackie Adenovirus Receptor Antikörper (AA 259-365)

Produktnummer ABIN7148649

Produktdetails anti-Coxsackie Adenovirus Receptor Antikörper

Target: Coxsackie Adenovirus Receptor (CXADR) (Coxsackie Virus and Adenovirus Receptor (CXADR))

Bindungsspezifität: AA 259-365

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Coxsackie Adenovirus Receptor Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Coxsackievirus and adenovirus receptor protein (259-365AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Coxsackie Adenovirus Receptor

Target: Coxsackie Adenovirus Receptor (CXADR) (Coxsackie Virus and Adenovirus Receptor (CXADR))

Andere Bezeichnung: CXADR (CXADR Produkte)

Hintergrund:

Background: Component of the epithelial apical junction complex that may function as an homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with AMICA1/JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, AMICA1 induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.

Aliases: 46 kD coxsackievirus and adenovirus receptor CAR protein antibody, 46 kD coxsackievirus and adenovirus receptor protein antibody, CAR antibody, CAR4/6 antibody, Coxsackie virus and adenovirus receptor antibody, Coxsackie virus B receptor antibody, Coxsackievirus and adenovirus receptor antibody, Coxsackievirus B adenovirus receptor antibody, Coxsackievirus B-adenovirus receptor antibody, CVB3 binding protein antibody, CVB3-binding protein antibody, Cxadr antibody, CXADR Ig like cell adhesion molecule antibody, CXAR_HUMAN antibody, hCAR antibody, HCVADR antibody

UniProt: P78310

Pathways: Cell-Cell Junction Organization