CRTC2 Antikörper (AA 180-372)

Produktnummer ABIN7148679

Produktdetails anti-CRTC2 Antikörper

Target: CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

Bindungsspezifität: AA 180-372

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRTC2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human CREB-regulated transcription coactivator 2 protein (180-372AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CRTC2

Target: CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

Andere Bezeichnung: CRTC2 (CRTC2 Produkte)

Synonyme: CRTC2 antikoerper, TORC-2 antikoerper, TORC2 antikoerper, 4632407F12Rik antikoerper, Torc2 antikoerper, mTORC2 antikoerper, RGD1308903 antikoerper, CREB regulated transcription coactivator 2 antikoerper, CRTC2 antikoerper, Crtc2 antikoerper

Hintergrund:

Background: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 \'Ser-133\' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).

Aliases: CREB regulated transcription coactivator 2 antibody, CREB-regulated transcription coactivator 2 antibody, CRTC2 antibody, CRTC2_HUMAN antibody, RP11-422P24.6 antibody, TORC-2 antibody, torc2 antibody, Transducer of CREB protein 2 antibody, Transducer of regulated cAMP response element-binding protein antibody, Transducer of regulated cAMP response element-binding protein (CREB) 2 antibody, Transducer of regulated cAMP response element-binding protein 2 antibody, Transducer of regulated CREB protein 2 antibody

UniProt: Q53ET0

Pathways: AMPK Signaling, Carbohydrate Homeostasis