Cullin 4B Antikörper (AA 1-200)
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- Target Alle Cullin 4B (CUL4B) Antikörper anzeigen
- Cullin 4B (CUL4B)
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Bindungsspezifität
- AA 1-200
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Cullin 4B Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human
- Aufreinigung
- Antigen Affinity Purified
- Immunogen
- Recombinant Human Cullin-4B protein (1-200AA)
- Isotyp
- IgG
- Top Product
- Discover our top product CUL4B Primärantikörper
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anti-Cullin 4B (CUL4B) (Internal Region) antibody
CUL4B Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin 4B (CUL4B) (AA 1-200) antibodyCUL4B Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin 4B (CUL4B) (AA 1-300) antibodyCUL4B Reaktivität: Human, Maus, Hund WB, IHC, IHC (p) Wirt: Maus Monoclonal 1C4 unconjugated
anti-Cullin 4B (CUL4B) (AA 250-278) antibodyCUL4B Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB42521 unconjugated
anti-Cullin 4B (CUL4B) (AA 1-913) antibodyCUL4B Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-Cullin 4B (CUL4B) antibodyCUL4B Reaktivität: Human, Maus ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin 4B (CUL4B) antibodyCUL4B Reaktivität: Human, Ratte, Zebrafisch (Danio rerio), Fisch WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin 4B (CUL4B) (AA 1-300) antibodyCUL4B Reaktivität: Human, Maus, Ratte, Hund, Affe WB Wirt: Maus Monoclonal 7F8 unconjugated
anti-Cullin 4B (CUL4B) (C-Term) antibodyCUL4B Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio) WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin 4B (CUL4B) antibodyCUL4B Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- Cullin 4B (CUL4B)
- Andere Bezeichnung
- CUL4B (CUL4B Produkte)
- Hintergrund
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Background: Core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition subunit. CUL4B may act within the complex as a scaffold protein, contributing to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Plays a role as part of the E3 ubiquitin-protein ligase complex in polyubiquitination of CDT1, histone H2A, histone H3 and histone H4 in response to radiation-induced DNA damage. Targeted to UV damaged chromatin by DDB2 and may be important for DNA repair and DNA replication. Required for ubiquitination of cyclin E, and consequently, normal G1 cell cycle progression. Regulates the mammalian target-of-rapamycin (mTOR) pathway involved in control of cell growth, size and metabolism. Specific CUL4B regulation of the mTORC1-mediated pathway is dependent upon 26S proteasome function and requires interaction between CUL4B and MLST8.
Aliases: CUL 4B antibody, CUL-4B antibody, CUL4B antibody, CUL4B_HUMAN antibody, Cullin-4B antibody, DKFZp686F1470 antibody, KIAA0695 antibody, MRXHF2 antibody, MRXSC antibody, SFM2 antibody
- UniProt
- Q13620
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