Cyclin H Antikörper (AA 261-319)

Produktnummer ABIN7148939

Produktdetails anti-Cyclin H Antikörper

Target: Cyclin H (CCNH)

Bindungsspezifität: AA 261-319

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin H Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Cyclin-H protein (261-319AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Cyclin H

Target: Cyclin H (CCNH)

Andere Bezeichnung: CCNH (CCNH Produkte)

Synonyme: zgc:114132 antikoerper, cak antikoerper, p34 antikoerper, p37 antikoerper, Cych antikoerper, ACYPI004637 antikoerper, ccnh antikoerper, Cyclin-H antikoerper, 142767_at antikoerper, CG7405 antikoerper, Dmel\\CG7405 antikoerper, CAK antikoerper, 6330408H09Rik antikoerper, AI661354 antikoerper, AV102684 antikoerper, AW538719 antikoerper, ccnh-A antikoerper, cyclin H antikoerper, cyclin-H antikoerper, Cyclin H antikoerper, CYclin H antikoerper, cyclin H L homeolog antikoerper, CCNH antikoerper, ccnh antikoerper, LOC5577539 antikoerper, Cych antikoerper, CycH antikoerper, cyh-1 antikoerper, Ccnh antikoerper, ccnh.L antikoerper

Hintergrund:

Background: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

Aliases: 6330408H09Rik antibody, AI661354 antibody, AV102684 antibody, AW538719 antibody, CAK antibody, CAK complex subunit antibody, ccnh antibody, CCNH_HUMAN antibody, CDK activating kinase antibody, CDK activating kinase complex subunit antibody, Cyclin dependent kinase activating kinase antibody, cyclin dependent kinase activating kinase complex subunit antibody, Cyclin H antibody, Cyclin-H antibody, CyclinH antibody, MO15 associated protein antibody, MO15-associated protein antibody, p34 antibody, p36 antibody, p37 antibody

UniProt: P51946

Pathways: Zellzyklus, Mitotic G1-G1/S Phases, M Phase