CST3 Antikörper

Produktnummer ABIN7148973

Produktdetails anti-CST3 Antikörper

Target: CST3 (Cystatin C (CST3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CST3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: Protein G purified

Immunogen: Recombinant Human Cystatin C protein

Klon: 3A1B7

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Recommended dilution:IHC:1:50-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CST3

Target: CST3 (Cystatin C (CST3))

Andere Bezeichnung: CST3 (CST3 Produkte)

Synonyme: armd11 antikoerper, fb51d07 antikoerper, wu:fb24g06 antikoerper, wu:fb51d07 antikoerper, wu:fc55f03 antikoerper, zgc:136227 antikoerper, ARMD11 antikoerper, CysC antikoerper, CYSC antikoerper, cystatin C antikoerper, cystatin C L homeolog antikoerper, cystatin C (amyloid angiopathy and cerebral hemorrhage) antikoerper, cystatin 3 antikoerper, CST3 antikoerper, cst3.L antikoerper, cst3 antikoerper, cystatin 3 antikoerper, Cst3 antikoerper

Hintergrund:

Background: Defects in CST3 are the cause of amyloidosis type 6 (AMYL6) [MIM:105150], also known as hereditary cerebral hemorrhage with amyloidosis (HCHWA), cerebral amyloid angiopathy (CAA) or cerebroarterial amyloidosis Icelandic type. AMYL6 is a hereditary generalized amyloidosis due to cystatin C amyloid deposition. Cystatin C amyloid accumulates in the walls of arteries, arterioles, and sometimes capillaries and veins of the brain, and in various organs including lymphoid tissue, spleen, salivary glands, and seminal vesicles. Amyloid deposition in the cerebral vessels results in cerebral amyloid angiopathy, cerebral hemorrhage and premature stroke. Cystatin C levels in the cerebrospinal fluid are abnormally low.Genetic variations in CST3 are associated with age-related macular degeneration type 11 (ARMD11) [MIM:611953]. ARMD is a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane.

Aliases: CysC,Cystatin-3,Gamma-trace,Neuroendocrine basic polypeptide,Post-gamma-globulin

UniProt: P01034