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CISH Antikörper (AA 1-257)

CISH Reaktivität: Human IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7149303
  • Target Alle CISH Antikörper anzeigen
    CISH (Cytokine Inducible SH2-Containing Protein (CISH))
    Bindungsspezifität
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-257
    Reaktivität
    • 24
    • 17
    • 15
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 24
    • 1
    Kaninchen
    Klonalität
    • 25
    Polyklonal
    Konjugat
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CISH Antikörper ist unkonjugiert
    Applikation
    • 16
    • 6
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Cytokine-inducible SH2-containing protein (1-257AA)
    Isotyp
    IgG
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  • Applikationshinweise
    Recommended dilution: IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    CISH (Cytokine Inducible SH2-Containing Protein (CISH))
    Andere Bezeichnung
    CISH (CISH Produkte)
    Synonyme
    CISH antikoerper, cis antikoerper, cish.a antikoerper, ptk9l antikoerper, twf1l antikoerper, wu:fk57g04 antikoerper, zgc:154062 antikoerper, zgc:91817 antikoerper, g18 antikoerper, socs antikoerper, cis-1 antikoerper, cish antikoerper, BACTS2 antikoerper, CIS antikoerper, CIS-1 antikoerper, G18 antikoerper, SOCS antikoerper, AI385595 antikoerper, CIS1 antikoerper, Cis antikoerper, F17 antikoerper, F23 antikoerper, cytokine inducible SH2 containing protein antikoerper, cytokine inducible SH2-containing protein antikoerper, CISH antikoerper, cish antikoerper, Cish antikoerper
    Hintergrund

    Background: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CIS is involved in the negative regulation of cytokines that signal through the JAK-STAT5 pathway such as erythropoietin, prolactin and interleukin 3 (IL3) receptor. Inhibits STAT5 trans-activation by suppressing its tyrosine phosphorylation. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

    Aliases: BACTS2 antibody, cis 1 antibody, CIS antibody, CIS-1 antibody, CIS1 antibody, Cish antibody, CISH_HUMAN antibody, Cytokine inducible inhibitor of signaling type 1B antibody, Cytokine inducible SH2 containing protein antibody, Cytokine-inducible SH2-containing protein antibody, G18 antibody, Protein G18 antibody, SOCS antibody, Suppressor of cytokine signaling antibody

    UniProt
    Q9NSE2
    Pathways
    JAK-STAT Signalweg, Response to Growth Hormone Stimulus
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