NCK1 Antikörper (AA 58-377)

Produktnummer ABIN7149352

Produktdetails anti-NCK1 Antikörper

Target: NCK1 (NCK Adaptor Protein 1 (NCK1))

Bindungsspezifität: AA 58-377

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Kreuzreaktivität: Human, Ratte

Aufreinigung: Antigen Affinity purified

Immunogen: Recombinant Human Cytoplasmic protein NCK1 protein (58-377AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu NCK1

Target: NCK1 (NCK Adaptor Protein 1 (NCK1))

Andere Bezeichnung: NCK1 (NCK1 Produkte)

Synonyme: NCK antikoerper, NCKalpha antikoerper, nck-1 antikoerper, NCK1 antikoerper, 6330586M15Rik antikoerper, D230010O13Rik antikoerper, Nck antikoerper, Nck-1 antikoerper, Nck1 antikoerper, nck antikoerper, nck1-a antikoerper, nck1-b antikoerper, nckalpha antikoerper, NCK adaptor protein 1 antikoerper, non-catalytic region of tyrosine kinase adaptor protein 1 antikoerper, NCK adaptor protein 1b antikoerper, NCK adaptor protein 1 L homeolog antikoerper, NCK1 antikoerper, Nck1 antikoerper, nck1b antikoerper, nck1.L antikoerper

Hintergrund:

Background: Adapter protein which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in the DNA damage response, not in the detection of the damage by ATM/ATR, but for efficient activation of downstream effectors, such as that of CHEK2. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling. Modulates the activation of EIF2AK2/PKR by dsRNA. May play a role in cell adhesion and migration through interaction with ephrin receptors.

Aliases: Cytoplasmic protein NCK1 antibody, Melanoma Nck protein antibody, MGC12668 antibody, NCK 1 antibody, NCK adaptor protein 1 antibody, NCK alpha antibody, NCK antibody, NCK tyrosine kinase antibody, Nck-1 antibody, NCK1 antibody, NCK1_HUMAN antibody, NCKalpha antibody, Non catalytic region of tyrosine kinase antibody, SH2/SH3 adaptor protein NCK alpha antibody, SH2/SH3 adaptor protein NCK-alpha antibody

UniProt: P16333

Pathways: T-Zell Rezeptor Signalweg, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals