DACH1 Antikörper (AA 166-369)
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- Target Alle DACH1 Antikörper anzeigen
- DACH1 (Dachshund 1 (DACH1))
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Bindungsspezifität
- AA 166-369
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DACH1 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Dachshund homolog 1 protein (166-369AA)
- Isotyp
- IgG
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- Applikationshinweise
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- DACH1 (Dachshund 1 (DACH1))
- Andere Bezeichnung
- DACH1 (DACH1 Produkte)
- Synonyme
- DACH antikoerper, AI182278 antikoerper, Dac antikoerper, Dach antikoerper, E130112M23Rik antikoerper, dach antikoerper, dachshund family transcription factor 1 antikoerper, dachshund 1 (Drosophila) antikoerper, dachshund family transcription factor 1 S homeolog antikoerper, dachshund homolog 1 antikoerper, DACH1 antikoerper, Dach1 antikoerper, dach1.S antikoerper, dach1 antikoerper, LOC100550020 antikoerper
- Hintergrund
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Background: Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator of SIX1, SIX6 and probably SIX5. Corepression of precursor cell proliferation in myoblasts by SIX1 is switched to coactivation through recruitment of EYA3 to the SIX1-DACH1 complex. Transcriptional activation seems also to involve association of CREBBP. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter (By similarity). Inhibits TGF-beta signaling through interaction with SMAD4 and NCOR1. Binds to chromatin DNA via its DACHbox-N domain (By similarity).
Aliases: DACH antibody, Dach1 antibody, DACH1_HUMAN antibody, Dachshund family transcription factor 1 antibody, dachshund homolog 1 (Drosophila) antibody, Dachshund homolog 1 antibody, Dachsund homolog 1 antibody, FLJ10138 antibody, OTTHUMP00000018494 antibody
- UniProt
- Q9UI36
- Pathways
- Feeding Behaviour
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