DOCK1 Antikörper (AA 1676-1865)
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- Target Alle DOCK1 Antikörper anzeigen
- DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))
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Bindungsspezifität
- AA 1676-1865
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DOCK1 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Dedicator of cytokinesis protein 1 protein (1676-1865AA)
- Isotyp
- IgG
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anti-Dedicator of Cytokinesis 1 (DOCK1) (C-Term) antibody
DOCK1 Reaktivität: Human WB, IF, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Dedicator of Cytokinesis 1 (DOCK1) (AA 698-803) antibodyDOCK1 Reaktivität: Human ELISA, WB Wirt: Maus Monoclonal 3D10 unconjugated
anti-Dedicator of Cytokinesis 1 (DOCK1) (C-Term) antibodyDOCK1 Reaktivität: Human, Maus, Ratte ELISA, WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Dedicator of Cytokinesis 1 (DOCK1) (AA 1645-2186) antibodyDOCK1 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Dedicator of Cytokinesis 1 (DOCK1) (C-Term) antibodyVerified DOCK1 Reaktivität: Human WB Wirt: Ziege Polyclonal unconjugated
anti-Dedicator of Cytokinesis 1 (DOCK1) (AA 1200-1435) antibodyDOCK1 Reaktivität: Human WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))
- Andere Bezeichnung
- DOCK1 (DOCK1 Produkte)
- Synonyme
- DOCK180 antikoerper, ced5 antikoerper, 9130006G06Rik antikoerper, AI854900 antikoerper, D630004B07Rik antikoerper, RGD1566072 antikoerper, dedicator of cytokinesis 1 antikoerper, dedicator of cytokinesis protein 1 antikoerper, dedicator of cyto-kinesis 1 antikoerper, DOCK1 antikoerper, Dock1 antikoerper, dock1 antikoerper, CpipJ_CPIJ002759 antikoerper
- Hintergrund
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Background: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed:19004829). Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 (PubMed:8657152).
Aliases: 180 kDa protein downstream of CRK antibody, Ced5 antibody, Dedicator of Cytokinesis 1 antibody, Dedicator of cytokinesis protein 1 antibody, DOCK 1 antibody, DOCK 180 antibody, DOCK1 antibody, DOCK1_HUMAN antibody, DOCK180 antibody
- UniProt
- Q14185
- Pathways
- Signaling of Hepatocyte Growth Factor Receptor
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