DOCK3 Antikörper (AA 1630-1934)

Produktnummer ABIN7149587

Produktdetails anti-DOCK3 Antikörper

Target: DOCK3 (Dedicator of Cytokinesis 3 (DOCK3))

Bindungsspezifität: AA 1630-1934

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DOCK3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Dedicator of cytokinesis protein 3 protein (1630-1934AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DOCK3

Target: DOCK3 (Dedicator of Cytokinesis 3 (DOCK3))

Andere Bezeichnung: DOCK3 (DOCK3 Produkte)

Synonyme: MOCA antikoerper, PBP antikoerper, mKIAA0299 antikoerper, dedicator of cytokinesis 3 antikoerper, similar to dedicator of cytokinesis 3 antikoerper, dedicator of cytokinesis protein 3 antikoerper, dedicator of cyto-kinesis 3 antikoerper, DOCK3 antikoerper, LOC561387 antikoerper, dock3 antikoerper, LOC100474164 antikoerper, Dock3 antikoerper

Hintergrund:

Background: Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP. Its interaction with presenilin proteins as well as its ability to stimulate Tau/MAPT phosphorylation suggest that it may be involved in Alzheimer disease. Ectopic expression in nerve cells decreases the secretion of beta-amyloid APBA1 protein and lowers the rate of cell-substratum adhesion, suggesting that it may affect the function of some small GTPase involved in the regulation of actin cytoskeleton or cell adhesion receptors (By similarity).

Aliases: DOCK3 antibody, KIAA0299 antibody, MOCADedicator of cytokinesis protein 3 antibody, Modifier of cell adhesion antibody, Presenilin-binding protein antibody, PBP antibody

UniProt: Q8IZD9