DHRS2 Antikörper (AA 1-300)

Produktnummer ABIN7149618

Produktdetails anti-DHRS2 Antikörper

Target: DHRS2 (Dehydrogenase/reductase (SDR Family) Member 2 (DHRS2))

Bindungsspezifität: AA 1-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DHRS2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Dehydrogenase/reductase SDR family member 2, mitochondrial protein (1-300AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DHRS2

Target: DHRS2 (Dehydrogenase/reductase (SDR Family) Member 2 (DHRS2))

Andere Bezeichnung: DHRS2 (DHRS2 Produkte)

Synonyme: DHRS2 antikoerper, HEP27 antikoerper, SDR25C1 antikoerper, 5430405K24Rik antikoerper, Hep27 antikoerper, dehydrogenase/reductase 4 antikoerper, dehydrogenase/reductase 2 antikoerper, dehydrogenase/reductase member 2 antikoerper, DHRS4 antikoerper, DHRS2 antikoerper, Dhrs2 antikoerper

Hintergrund:

Background: Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.

Aliases: DHRS2 antibody, SDR25C1 antibody, Dehydrogenase/reductase SDR family member 2 antibody, mitochondrial antibody, EC 1.1.1.- antibody, Dicarbonyl reductase HEP27 antibody, Protein D antibody, Short chain dehydrogenase/reductase family 25C member 1 antibody

UniProt: Q13268

Pathways: C21-Steroid Hormone Metabolic Process