DKK2 Antikörper (AA 34-259)
-
- Target Alle DKK2 Antikörper anzeigen
- DKK2 (Dickkopf 2 Homolog (DKK2))
-
Bindungsspezifität
- AA 34-259
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser DKK2 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Dickkopf-related protein 2 protein (34-259AA)
- Isotyp
- IgG
-
-
- Applikationshinweise
- Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Target
- DKK2 (Dickkopf 2 Homolog (DKK2))
- Andere Bezeichnung
- DKK2 (DKK2 Produkte)
- Synonyme
- DKK-2 antikoerper, Dkk4 antikoerper, zgc:171574 antikoerper, dickkopf WNT signaling pathway inhibitor 2 antikoerper, DKK2 antikoerper, Dkk2 antikoerper, dkk2 antikoerper
- Hintergrund
-
Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Aliases: Dickkopf 2 antibody, Dickkopf gene 2 antibody, Dickkopf homolog 2 antibody, Dickkopf related protein 2 antibody, Dickkopf WNT signaling pathway inhibitor 2 antibody, Dickkopf-2 antibody, Dickkopf-related protein 2 antibody, Dickkopf2 antibody, DKK 2 antibody, Dkk-2 antibody, Dkk2 antibody, DKK2_HUMAN antibody, hDkk 2 antibody, hDkk-2 antibody, hDkk2 antibody
- UniProt
- Q9UBU2
- Pathways
- WNT Signalweg
-