DIS3L2 Antikörper (AA 201-400) (Biotin)

Produktnummer ABIN7150018

Produktdetails anti-DIS3L2 Antikörper (Biotin)

Target: DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))

Bindungsspezifität: AA 201-400

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DIS3L2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human DIS3-like exonuclease 2 protein (201-400AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DIS3L2

Target: DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))

Andere Bezeichnung: DIS3L2 (DIS3L2 Produkte)

Synonyme: RGD1560168 antikoerper, DIS3L2 antikoerper, DKFZp469O0522 antikoerper, FAM6A antikoerper, PRLMNS antikoerper, hDIS3L2 antikoerper, 4930429A22Rik antikoerper, 8030493P09Rik antikoerper, DIS3-like 3'-5' exoribonuclease 2 antikoerper, DIS3 like 3'-5' exoribonuclease 2 antikoerper, DIS3-like exonuclease 2 antikoerper, Dis3l2 antikoerper, DIS3L2 antikoerper, LOC100344728 antikoerper

Hintergrund:

Background: 3\'-5\'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3\' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3\'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation.

Aliases: DI3L2_HUMAN antibody, DIS3 L2 antibody, DIS3 mitotic control homolog (S. cerevisiae) like 2 antibody, DIS3 mitotic control homolog like 2 antibody, DIS3-like exonuclease 2 antibody, Dis3l2 antibody, FLJ36974 antibody, MGC42174 antibody

UniProt: Q8IYB7

Pathways: Stem Cell Maintenance