DDR2 Antikörper (AA 447-540)

Produktnummer ABIN7150025

Produktdetails anti-DDR2 Antikörper

Target: DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))

Bindungsspezifität: AA 447-540

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Discoidin domain-containing receptor 2 protein (447-540AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DDR2

Target: DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))

Andere Bezeichnung: DDR2 (DDR2 Produkte)

Synonyme: MIG20a antikoerper, NTRKR3 antikoerper, TKT antikoerper, TYRO10 antikoerper, AW495251 antikoerper, Ntrkr3 antikoerper, tyro10 antikoerper, DDR2 antikoerper, Tyro10 antikoerper, ddr2 antikoerper, si:ch211-193c2.1 antikoerper, discoidin domain receptor tyrosine kinase 2 antikoerper, discoidin domain receptor family, member 2 antikoerper, discoidin domain receptor family, member 2, like antikoerper, DDR2 antikoerper, Ddr2 antikoerper, ddr2l antikoerper

Hintergrund:

Background: Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. Required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. Promotes fibroblast migration and proliferation, and thereby contributes to cutaneous wound healing.

Aliases: CD167 antigen-like family member B antibody, CD167b antibody, CD167b antigen antibody, Cell migration inducing protein 20 antibody, DDR 2 antibody, DDR2 antibody, DDR2_HUMAN antibody, Discoidin domain containing receptor 2 antibody, Discoidin domain receptor 2 antibody, Discoidin domain receptor family member 2 antibody, discoidin domain receptor tyrosine kinase 2 antibody, Discoidin domain-containing receptor 2 antibody, discoidin domain-containing receptor tyrosine kinase 2 antibody, Hydroxyaryl protein kinase antibody, MIG20a antibody, Migration inducing gene 16 protein antibody, Neurotrophic tyrosine kinase antibody, Neurotrophic tyrosine kinase receptor related 3 antibody, NTRKR 3 antibody, NTRKR3 antibody, Receptor protein tyrosine kinase TKT antibody, Receptor protein-tyrosine kinase TKT antibody, Receptor related 3 antibody, receptor-related 3 antibody, TKT antibody, TYRO 10 antibody, TYRO10 antibody, Tyrosine kinase receptor related to neurotrophic TRK antibody, Tyrosine protein kinase TYRO 10 antibody, Tyrosine protein kinase TYRO10 antibody, Tyrosine-protein kinase TYRO10 antibody, Tyrosylprotein kinase antibody

UniProt: Q16832

Pathways: RTK Signalweg