Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

ZRANB3 Antikörper (AA 370-624)

ZRANB3 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7150120
  • Target Alle ZRANB3 Produkte
    ZRANB3 (Zinc Finger, RAN-Binding Domain Containing 3 (ZRANB3))
    Bindungsspezifität
    • 4
    • 1
    • 1
    • 1
    • 1
    AA 370-624
    Reaktivität
    • 9
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 9
    Kaninchen
    Klonalität
    • 9
    Polyklonal
    Konjugat
    • 5
    • 2
    • 1
    • 1
    Dieser ZRANB3 Antikörper ist unkonjugiert
    Applikation
    • 5
    • 3
    • 1
    ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human DNA annealing helicase and endonuclease ZRANB3 protein (370-624AA)
    Isotyp
    IgG
  • Applikationshinweise
    Recommended dilution: IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    ZRANB3 (Zinc Finger, RAN-Binding Domain Containing 3 (ZRANB3))
    Andere Bezeichnung
    ZRANB3 (ZRANB3 Produkte)
    Synonyme
    4933425L19Rik antikoerper, AH2 antikoerper, AI316834 antikoerper, C730006D09 antikoerper, zinc finger RANBP2-type containing 3 antikoerper, zinc finger, RAN-binding domain containing 3 antikoerper, ZRANB3 antikoerper, Zranb3 antikoerper
    Hintergrund

    Background: DNA annealing helicase and endonuclease required to maintain genome stability at stalled or collapsed replication forks by facilitating fork restart and limiting inappropriate recombination that could occur during template switching events. Recruited to the sites of stalled DNA replication by polyubiquitinated PCNA and acts as a structure-specific endonuclease that cleaves the replication fork D-loop intermediate, generating an accessible 3\\\'-OH group in the template of the leading strand, which is amenable to extension by DNA polymerase. In addition to endonuclease activity, also catalyzes the fork regression via annealing helicase activity in order to prevent disintegration of the replication fork and the formation of double-strand breaks.

    Aliases: 4933425L19Rik antibody, AH2 antibody, Annealing helicase 2 antibody, DNA annealing helicase and endonuclease ZRANB3 antibody, MGC105033 antibody, MGC75012 antibody, OTTHUMP00000197449 antibody, Zinc finger Ran-binding domain-containing protein 3 antibody, Zinc finger, RAN- binding domain containing 3 antibody, ZRAB3_HUMAN antibody, Zranb3 antibody

    UniProt
    Q5FWF4
Sie sind hier:
Kundenservice