LIG3 Antikörper (AA 809-928)

Produktnummer ABIN7150193

Produktdetails anti-LIG3 Antikörper

Target: LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

Bindungsspezifität: AA 809-928

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LIG3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human DNA ligase 3 protein (809-928AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu LIG3

Target: LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

Andere Bezeichnung: LIG3 (LIG3 Produkte)

Synonyme: orf36 antikoerper, DDBDRAFT_0218523 antikoerper, DDBDRAFT_0232266 antikoerper, DDB_0218523 antikoerper, DDB_0232266 antikoerper, LIG3 antikoerper, wu:fb12c02 antikoerper, wu:fd10b03 antikoerper, wu:fm79b09 antikoerper, LIG2 antikoerper, D11Wsu78e antikoerper, An02g06890 antikoerper, AO090003000668 antikoerper, lig3 antikoerper, DNA ligase III antikoerper, BRCT domain-containing protein antikoerper, DNA ligase 3 antikoerper, ligase III, DNA, ATP-dependent antikoerper, ligase III, DNA, ATP-dependent L homeolog antikoerper, orf36 antikoerper, lig3 antikoerper, LIG3 antikoerper, Lig3 antikoerper, Bm1_22840 antikoerper, ANI_1_2644024 antikoerper, AOR_1_1174154 antikoerper, LOC100634887 antikoerper, lig3.L antikoerper

Hintergrund:

Background: Isoform 3 functions as heterodimer with DNA-repair protein XRCC1 in the nucleus and can correct defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. Isoform 1 is targeted to mitochondria, where it functions as DNA ligase in mitochondrial base-excision DNA repair (PubMed:10207110, PubMed:24674627).

Aliases: D11Wsu78e antibody, DNA ligase antibody, DNA ligase 3 antibody, DNA ligase III antibody, DNLI3_HUMAN antibody, LIG 3 antibody, LIG2 antibody, LIG3 antibody, Ligase II, DNA, ATP dependent antibody, Ligase III DNA ATP dependent antibody, MGC78176 antibody, OTTMUSP00000000875 antibody, Polydeoxyribonucleotide synthase [ATP] 3 antibody, Polydeoxyribonucleotide synthase [ATP] antibody, Polydeoxyribonucleotide synthase antibody, RP23-316C11.6 antibody

UniProt: P49916

Pathways: DNA Reparatur