DMAP1 Antikörper (AA 250-300)

Produktnummer ABIN7150197

Produktdetails anti-DMAP1 Antikörper

Target: DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

Bindungsspezifität: AA 250-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DMAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human DNA methyltransferase 1-associated protein 1 protein (250-300AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DMAP1

Target: DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

Andere Bezeichnung: DMAP1 (DMAP1 Produkte)

Synonyme: Afu4g07380 antikoerper, T8I13.5 antikoerper, DNMAP1 antikoerper, DNMTAP1 antikoerper, EAF2 antikoerper, MEAF2 antikoerper, SWC4 antikoerper, zgc:55593 antikoerper, dnmap1 antikoerper, dnmtap1 antikoerper, eaf2 antikoerper, meaf2 antikoerper, swc4 antikoerper, 1500016M21Rik antikoerper, Dmtap1 antikoerper, mKIAA1425 antikoerper, DNA methyltransferase 1-associated protein DMAP1 antikoerper, DNA methyltransferase 1-associated protein 1 antikoerper, DNA methyltransferase 1 associated protein 1 antikoerper, myb-like transcription factor family protein antikoerper, DNA methyltransferase 1 associated protein 1 L homeolog antikoerper, AFUA_4G07380 antikoerper, NFIA_108840 antikoerper, ACLA_046700 antikoerper, CpipJ_CPIJ017959 antikoerper, Bm1_47540 antikoerper, PMAA_026820 antikoerper, AFLA_112450 antikoerper, TSTA_072020 antikoerper, BDBG_02603 antikoerper, AT2G47210 antikoerper, CpipJ_CPIJ007438 antikoerper, DMAP1 antikoerper, dmap1 antikoerper, dmap1.L antikoerper, Dmap1 antikoerper

Hintergrund:

Background: Involved in transcription repression and activation. Its interaction with HDAC2 may provide a mechanism for histone deacetylation in heterochromatin following replication of DNA at late firing origins. Can also repress transcription independently of histone deacetylase activity. May specifically potentiate DAXX-mediated repression of glucocorticoid receptor-dependent transcription. Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Participates in the nuclear localization of URI1 and increases its transcriptional corepressor activity.

Aliases: DMAP1 antibody, KIAA1425DNA methyltransferase 1-associated protein 1 antibody, DNMAP1 antibody, DNMT1-associated protein 1 antibody

UniProt: Q9NPF5